Treatment strategies for antibody-mediated rejection in kidney transplantation and its prevention

Pierpaolo Di Cocco, Alberto Fratti, Kerim B. Kaylan, Ivo G. Tzvetanov, Enrico Benedetti. “Treatment strategies for antibody-mediated rejection in kidney transplantation and its prevention.” OBM Transplantation 4(3): 16. September 2020.


This article reviews the current treatment strategies of antibody-mediated rejection in kidney transplantation, which is increasingly recognized as the leading immunological cause of graft failure. The pathophysiologic complexity of this condition poses significant challenges for its treatment; however, progress toward advancing our understanding of its pathogenesis and diagnosis will allow for identification of new therapeutic targets. Emphasis is also given to prevention, which is mainly based on careful assessment of the transplant candidate and immunological risk stratification.

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I am an MD/PhD student at the University of Illinois College of Medicine. My doctoral work focused on tissue engineering approaches to study stem and progenitor cell fate in the developing liver. Learn more.



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